Maintaining the trend of classic movies, there is a 1931 version of Dr. Jekyll and Mr. Hyde, released by Paramount, directed by Rouben Mamoulian and starring Fredric March.
The story of Jekyll and Hyde is based on a tale by Robert Louis Stephenson, Strange Case of Dr Jekyll and Mr Hyde.
In this story, a scientist devises a potion that will separate his evil, base nature from his normal self. The result is that while his regular self, Dr. Jekyll, remains human (both good and evil), his evil nature forms a new personality, Dr. Hyde; both occupy the same body.
Eventually, Hyde becomes more and more out of control, and Jekyll knows that some day he will take over the body completely.
While many movies portray Hyde as being monstrous in appearance, in the book he merely looks sinister, and is short.
The influence of these characters on the appearance of Holt Hyde is unknown, though he has many elements of duality or being patched together: his hair is two colors, he has a yin-yang tattoo, and his pet is a chameleon.